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The adsorption of progesterone onto mineral surfaces imaged with high-resolution atomic force microscopy

¹ Interface Analysis Centre, University of Bristol, Bristol, UK
² Department of Physics, University of Bristol, Bristol, UK
³ Department of Earth Sciences, University of Bristol, Bristol, UK

^* E-mail: b.goritschnig{at}bristol.ac.uk

ABSTRACT

Atomic force microscopy (AFM) has been used to monitor the appearance and behaviour of the hormone progesterone on mineral surfaces, including mica and highly oriented pyrolytic graphite (HOPG). Different solvents have been used resulting in various features on the two substrates. After the application of 254 nm ultra-violet (UV) light, changes in structure of the adsorbed hormone have been observed. To understand the reactions at the progesterone-mica interface in aqueous solution, adsorption has been studied in situ with AFM.